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Wednesday, August 15, 2012

Trihist-D

Generic Name: pheniramine/ pyrilamine/ phenyltoloxamine/ phenylpropanolamine (fen IR a meen/pie RILL a meen/fen ill toe LOX a meen/fen ill proe pa NOLE a meen)

Brand Names: Delhist D, Delhistine D, Histine-D, Iohist D, KG-Hist D, Liqui-Histine-D, Metahistine D, Multihist D, Multihistamine-D, Poly-D, Poly-Histine-D, Prohistine-D, Trihist-D

What is Trihist-D (pheniramine/ pyrilamine/ phenyltoloxamine/ phenylpropanolamine)?

Pheniramine, pyrilamine, and phenyltoloxamine are antihistamines. They block the effects of the naturally occurring chemical histamine in the body. Pheniramine, pyrilamine, and phenyltoloxamine prevent sneezing; itchy, watery eyes and nose; and other symptoms of allergies and hay fever.

Phenylpropanolamine is a decongestant. It constricts (shrinks) blood vessels (veins and arteries). This reduces the blood flow to certain areas and allows nasal and respiratory (breathing) passages to open up.

Pheniramine/pyrilamine/phenyltoloxamine/phenylpropanolamine is used to treat nasal congestion and sinusitis (inflammation of the sinuses) associated with allergies, hay fever, and the common cold.

Phenylpropanolamine, an ingredient in this product, has been associated with an increased risk of hemorrhagic stroke (bleeding into the brain or into tissue surrounding the brain) in women. Men may also be at risk. Although the risk of hemorrhagic stroke is low, the U.S. Food and Drug Administration (FDA) recommends that consumers not use any products that contain phenylpropanolamine.

Pheniramine/pyrilamine/phenyltoloxamine/phenylpropanolamine may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Trihist-D (pheniramine/ pyrilamine/ phenyltoloxamine/ phenylpropanolamine)?

Use caution when driving, operating machinery, or performing other hazardous activities. Pheniramine/pyrilamine/phenyltoloxamine/phenylpropanolamine may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while taking this medication.

Do not take more of this medication than is recommended. If your symptoms do not improve, or if they worsen, talk to your doctor.

Who should not take Trihist-D (pheniramine/ pyrilamine/ phenyltoloxamine/ phenylpropanolamine)?

Do not take pheniramine/pyrilamine/phenyltoloxamine/phenylpropanolamine if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects.

Before taking this medication, tell your doctor if you have

kidney disease,

liver disease,

diabetes,

glaucoma,

any type of heart disease or high blood pressure,

thyroid disease,

emphysema or chronic bronchitis, or

difficulty urinating or an enlarged prostate.

You may not be able to take pheniramine/pyrilamine/phenyltoloxamine/phenylpropanolamine, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.

Pheniramine/pyrilamine/phenyltoloxamine/phenylpropanolamine is in the FDA pregnancy category B. This means that it is unlikely to harm an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant. Pheniramine/pyrilamine/phenyltoloxamine/phenylpropanolamine passes into breast milk and may harm a nursing infant. Do not take this medication without first talking to your doctor if you are breast-feeding a baby. If you are over 65 years of age, you may be more likely to experience side effects from pheniramine/pyrilamine/phenyltoloxamine/phenylpropanolamine. You may require a lower dose of this medication. Read the package label for directions or consult your doctor or pharmacist before treating a child with this medication. Children are more susceptible than adults to the effects of medicines and may have unusual reactions.

How should I take Trihist-D (pheniramine/ pyrilamine/ phenyltoloxamine/ phenylpropanolamine)?

Take pheniramine/pyrilamine/phenyltoloxamine/phenylpropanolamine exactly as directed. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass of water. Do not crush, chew, or break the long-acting or sustained-release forms of this medication. Swallow them whole. If you are unsure about the formulation of the medicine, ask your pharmacist for help.

If you cannot swallow the tablets or capsules, look for a liquid form of this medication.

To ensure that you get a correct dose, measure the liquid form of pheniramine/pyrilamine/phenyltoloxamine/phenylpropanolamine with a special dose-measuring spoon or cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one.

Do not take more of this medication than is recommended. An overdose can cause serious harm.

Do not take pheniramine/pyrilamine/phenyltoloxamine/phenylpropanolamine for longer than 7 days in a row. If your symptoms do not improve, if they get worse, or if you have a fever, talk to your doctor.

Store pheniramine/pyrilamine/phenyltoloxamine/phenylpropanolamine at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication.

What happens if I overdose?

Seek emergency medical attention.

Symptoms of a pheniramine/pyrilamine/phenyltoloxamine/phenylpropanolamine overdose include a dry mouth, large pupils, flushing, nausea, and vomiting.

What should I avoid while taking Trihist-D (pheniramine/ pyrilamine/ phenyltoloxamine/ phenylpropanolamine)?

Trihist-D (pheniramine/ pyrilamine/ phenyltoloxamine/ phenylpropanolamine) side effects

Serious side effects are unlikely to occur. Stop taking pheniramine/pyrilamine/phenyltoloxamine/phenylpropanolamine and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives).

Other, less serious side effects may be more likely to occur. Continue to take pheniramine/pyrilamine/phenyltoloxamine/phenylpropanolamine and talk to your doctor or try another similar medication if you experience

dryness of the eyes, nose, and mouth;

drowsiness or dizziness;

blurred vision;

difficulty urinating; or

excitation in children.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect Trihist-D (pheniramine/ pyrilamine/ phenyltoloxamine/ phenylpropanolamine)?

Do not take other over-the-counter cough, cold, allergy, diet, or sleep aids while taking pheniramine/pyrilamine/phenyltoloxamine/phenylpropanolamine without first talking to your doctor or pharmacist. Other medications may also contain pheniramine, pyrilamine, phenyltoloxamine, phenylpropanolamine, or other similar drugs. You may accidentally take too much of these medicines.

Pheniramine/pyrilamine/phenyltoloxamine/phenylpropanolamine may increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, other antihistamines, pain relievers, anxiety medicines, seizure medicines, and muscle relaxants. Dangerous sedation, dizziness, or drowsiness may occur if pheniramine/pyrilamine/phenyltoloxamine/phenylpropanolamine is taken with any of these medications.

Drugs other than those listed here may also interact with pheniramine/pyrilamine/phenyltoloxamine/phenylpropanolamine. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including herbal products.

More Trihist-D resources

Trihist-D Drug Interactions
Trihist-D Support Group
0 Reviews for Trihist-D - Add your own review/rating

Compare Trihist-D with other medications

Allergies
Eye Dryness/Redness
Eye Redness/Itching
Hay Fever
Nasal Congestion
Rhinorrhea
Sinusitis
Upper Respiratory Tract Infection

Where can I get more information?

Your pharmacist has additional information about pheniramine/pyrilamine/phenyltoloxamine/phenylpropanolamine written for health professionals that you may read.

What does my medication look like?

Pheniramine/pyrilamine/phenyltoloxamine/phenylpropanolamine is available with a prescription under the brand names Poly-Histine-D (capsules and elixir) and Liqui-Histine Elixir. Other brand or generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

Friday, August 10, 2012

Kaopectate

Generic Name: bismuth subsalicylate (BIZ muth sub sa LISS i late)

Brand Names: Bismarex, Bismatrol, Bismatrol Maximum Strength, Kao-Tin Bismuth Subsalicylate Formula, Kaopectate, Maalox Total Stomach Relief, Peptic Relief, Pepto-Bismol, Pepto-Bismol Maximum Strength, Pink Bismuth

What is Kaopectate (bismuth subsalicylate)?

Bismuth subsalicylate is an antacid and anti-diarrhea medication.

Bismuth subsalicylate is used to treat diarrhea, nausea, heartburn, indigestion, and upset stomach.

Bismuth subsalicylate may also be used for purposes not listed in this medication guide.

What is the most important information I should know about Kaopectate (bismuth subsalicylate)?

This medication should not be given to a child or teenager who has a fever, especially if the child also has flu symptoms or chicken pox. Salicylates can cause a serious and sometimes fatal condition called Reye's syndrome in children. You should not use bismuth subsalicylate if you have a stomach ulcer, a recent history of stomach or intestinal bleeding, or if you are allergic to salicylates such as aspirin, Doan's Extra Strength, Salflex, Tricosal, and others.

Do not take more than 8 doses in one day (24 hours).

Bismuth subsalicylate can cause you to have a black or darkened tongue. This is a harmless side effect.

This medication can also cause unusual results with certain medical tests, thyroid scans, or stomach x-rays. Tell any doctor who treats you that you have recently taken bismuth subsalicylate.

What should I discuss with my health care provider before taking Kaopectate (bismuth subsalicylate)?

This medication should not be given to a child or teenager who has a fever, especially if the child also has flu symptoms or chicken pox. Subsalicylate can cause a serious and sometimes fatal condition called Reye's syndrome in children. You should not use bismuth subsalicylate if you are allergic to it, or if you have:

a stomach ulcer;

a recent history of stomach or intestinal bleeding; or

if you are allergic to salicylates such as aspirin, Doan's Extra Strength, Salflex, Tricosal, and others.

Ask a doctor or pharmacist if it is safe for you to take this medicine if you have:

fever;

mucus in your stools;

diabetes;

arthritis; or

gout.

Do not take bismuth subsalicylate without medical advice if you are pregnant. Bismuth subsalicylate can pass into breast milk and may harm a nursing baby. Do not use this medication without medical advice if you are breast-feeding a baby.

How should I take Kaopectate (bismuth subsalicylate)?

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Do not take more than 8 doses in one day (24 hours). Shake the liquid medicine well just before you measure a dose. Measure the liquid with a special dose-measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

The chewable tablet must be chewed before you swallow it.

Bismuth subsalicylate can cause you to have a black or darkened tongue. This is a harmless side effect.

This medication can also cause unusual results with certain medical tests, thyroid scans, or stomach x-rays. Tell any doctor who treats you that you have recently taken bismuth subsalicylate.

Store at room temperature away from moisture and heat. Do not freeze.

What happens if I miss a dose?

Since bismuth subsalicylate is taken as needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose. Do not take more than 8 doses in one day (24 hours).

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include increased thirst, anxiety, muscle spasm, ringing in your ears, dizziness, confusion, severe headache, problems with speech or vision, severe stomach pain, or worsening diarrhea or vomiting.

What should I avoid while taking Kaopectate (bismuth subsalicylate)?

Ask your doctor or pharmacist before taking other antacids or diarrhea medications together with bismuth subsalicylate.

Kaopectate (bismuth subsalicylate) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop taking this medicine and call your doctor at once if you have a serious side effect such as:

hearing loss or ringing in your ears;

diarrhea lasting longer than 2 days; or

worsened stomach symptoms.

Less serious side effects include:

constipation;

dark colored stools; or

black or darkened tongue.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Kaopectate (bismuth subsalicylate)?

Ask a doctor or pharmacist if it is safe for you to use bismuth subsalicylate if you are also using any of the following drugs:

a blood thinner such as warfarin (Coumadin, Jantoven);

insulin or oral diabetes medications;

probenecid (Benemid);

an antibiotic such as doxycycline (Doryx, Oracea, Periostat, Vibramycin), minocycline (Dynacin, Minocin, Solodyn), or tetracycline (Ala-Tet, Brodspec, Panmycin, Sumycin, Tetracap);

medication used to prevent blood clots, such as alteplase (Activase), tenecteplase (TNKase), urokinase (Abbokinase); or

other salicylates such as aspirin, Nuprin Backache Caplet, Kaopectate, KneeRelief, Pamprin Cramp Formula, Pepto-Bismol, Tricosal, Trilisate, and others.

This list is not complete and other drugs may interact with bismuth subsalicylate. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More Kaopectate resources

Kaopectate Side Effects (in more detail)
Kaopectate Use in Pregnancy & Breastfeeding
Kaopectate Drug Interactions
Kaopectate Support Group
0 Reviews for Kaopectate - Add your own review/rating

Kaopectate Advanced Consumer (Micromedex) - Includes Dosage Information

Kaopectate MedFacts Consumer Leaflet (Wolters Kluwer)

Bismuth Subsalicylate Professional Patient Advice (Wolters Kluwer)

Bismatrol Chewable Tablets MedFacts Consumer Leaflet (Wolters Kluwer)

Compare Kaopectate with other medications

Diarrhea
Diarrhea, Chronic
Helicobacter Pylori Infection
Indigestion
Lymphocytic Colitis

Where can I get more information?

Your pharmacist can provide more information about bismuth subsalicylate.

See also: Kaopectate side effects (in more detail)

Tuesday, August 7, 2012

Sodium Sulfacetamide and Sulfur Aqueous Gel

Dosage Form: gel
10% Sodium Sulfacetamide and Sulfur 5% Aqueous Gel (in a Urea vehicle)

Rx only

DESCRIPTION: Sodium sulfacetamide is a sulfonamide with antibacterial activity. Sulfur acts as a keratolytic agent. Chemically, sodium sulfacetamide is N-[(4-aminophenyl)sulfonyl]-acetamide, monosodium salt, monohydrate. The structural formula is:

Each mL of 10% Sodium Sulfacetamide 5% Sulfur Aqueous Gel (in a Urea vehicle) contains 100 mg of sodium sulfacetamide and 50 mg of sulfur in an emulsion base containing 10% Urea, propylene glycol, isopropyl myristate, mineral oil, polysorbate 60, sorbitan monostearate, cetyl alcohol, cocoglycerides, stearyl alcohol, benzyl alcohol, glyceryl stearate and PEG 100 stearate, dimethicone, fragrance, disodium EDTA, xanthan gum, zinc pyrithione, sodium thiosulfate, purified water, magnesium aluminum silicate, and methyl paraben.

CLINICAL PHARMACOLOGY: The most widely accepted mechanism of action of sulfonamides is the Woods-Fildes theory, which is based on the fact that sulfonamides act as competitive antagonists to para-aminobenzoic acid (PABA), an essential component for bacterial growth. While absorption through intact skin has not been determined, sodium sulfacetamide is readily absorbed from the gastrointestinal tract when taken orally and excreted in the urine, largely unchanged. The biological half-life has variously been reported as 7 to 12.8 hours. The exact mode of action of sulfur in the treatment of acne is unknown, but it has been reported that it inhibits the growth of Propionibacterium acnes and the formation of free fatty acids.

INDICATIONS: 10% Sodium Sulfacetamide 5% Sulfur Aqueous Gel (in a Urea vehicle) is indicated in the topical control of acne vulgaris, acne rosacea and seborrheic dermatitis.

CONTRAINDICATIONS: 10% Sodium Sulfacetamide 5% Sulfur Aqueous Gel (in a Urea vehicle) is contraindicated for patients having known hypersensitivity to sulfonamides, sulfur or any other component of this preparation. 10% Sodium Sulfacetamide 5% Sulfur Aqueous Gel (in a Urea vehicle) is not to be used in patients with kidney disease.

WARNINGS: Rarely, sensitivity to sodium sulfacetamide may occur. Therefore, caution and careful supervision should be observed when prescribing this drug tor patients who may be prone to hypersensitivity to topical sulfonamides. Systemic toxic reactions such as agranulocytosis, acute hemolytic anemia, purpura hemorrhagica, drug fever, jaundice, and contact dermatitis indicate hypersensitivity to sulfonamides. Use particular caution on areas of denuded or abraded skin.

FOR EXTERNAL USE ONLY. Keep away from eyes.

Keep out of reach of children. Keep tube tightly closed.

PRECAUTIONS: General - If irritation develops, use of the product should be discontinued and appropriate therapy instituted. Patients should be carefully observed for possible local irritation or sensitization during long-term therapy. The object of this therapy is to achieve desquamation without irritation, but sodium sulfacetamide and sulfur can cause reddening and scaling of the epidermis. These side effects are not unusual in the treatment of acne vulgaris, but patients should be cautioned about the possibility.

Information for Patients - Avoid contact with eyes, eyelids, lips and mucous membranes. If accidental contact occurs, rinse with water. If excessive irritation develops, discontinue use and consult your physician.

Carcinogenesis, Mutagenesis and Impairment of Fertility - Long-term studies in animals have not been performed to evaluate carcinogenic potential.

Pregnancy - Category C. Animal reproduction studies have not been conducted with 10% Sodium Sulfacetamide 5% Sulfur Aqueous Gel (in a Urea vehicle). It is also not known whether 10% Sodium Sulfacetamide 5% Sulfur Aqueous Gel (in a Urea vehicle) can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. 10% Sodium Sulfacetamide 5% Sulfur Aqueous Gel (in a Urea vehicle) should be given to a pregnant woman only if clearly needed.

Nursing Mothers - It is not known whether sodium sulfacetamide is excreted in human milk following topical use of 10% Sodium Sulfacetamide 5% Sulfur Aqueous Gel (in a Urea vehicle). However, small amounts of orally administered sulfonamides have been reported to be excreted in human milk. For this reason, and because many drugs are excreted in human milk, caution should be exercised when 10% Sodium Sulfacetamide 5% Sulfur Aqueous Gel (in a Urea vehicle) is administered to a nursing woman.

Pediatric Use: Safety and effectiveness in children under the age of 12 years have not been established.

ADVERSE REACTIONS: Rarely, sodium sulfacetamide may cause local irritation.

Call your physician for medical advice about side effects.

DOSAGE AND ADMINISTRATION:

10% Sodium Sulfacetamide 5% Sulfur Aqueous Gel (in a Urea vehicle): Cleanse affected areas. Apply a thin film into affected areas 1 to 3 times daily, or as directed by a physician.

HOW SUPPLIED:

10% Sodium Sulfacetamide 5% Sulfur Aqueous Gel (in a Urea vehicle): is available in a 1.5 fl. oz (45 g) tube, NDC 42808-0111-45

Store 10% Sodium Sulfacetamide 5% Sulfur Aqueous Gel (in a Urea vehicle): at 15 to 30°C (59 to 86°F).

Protect from freezing.

Manufactured in the U.S.A. for Exact-Rx, Inc., Melville, NY 11747

00-0111-45-205-00

Iss:6/11

PACKAGE LABEL - 1.5 oz (45 g)

For External Use Only

NDC 42808-0111-45 Rx Only

Sodium

Sulfacetamide

& Sulfur

(Sodium Sulfacetamide 10%

& Sulfur 5% in a Urea Vehicle)

10%/5%

AQUEOUS GEL

Exact-Rx.

INCORPORATED

Net Wt. 1.5 oz (45 g)

SODIUM SULFACETAMIDE, SULFUR
sodium sulfacetamide, sulfur gel

Product Information
Product Type	HUMAN PRESCRIPTION DRUG	NDC Product Code (Source)	42808-111
Route of Administration	TOPICAL	DEA Schedule

Active Ingredient/Active Moiety
Ingredient Name	Basis of Strength	Strength
SULFACETAMIDE SODIUM (SULFACETAMIDE)	SULFACETAMIDE SODIUM	100 mg in 1 g
SULFUR (SULFUR)	SULFUR	50 mg in 1 g

Inactive Ingredients
Ingredient Name	Strength
UREA
PROPYLENE GLYCOL
ISOPROPYL MYRISTATE
MINERAL OIL
POLYSORBATE 60
SORBITAN MONOSTEARATE
CETYL ALCOHOL
COCO-GLYCERIDES
STEARYL ALCOHOL
BENZYL ALCOHOL
GLYCERYL MONOSTEARATE
POLYOXYL 100 STEARATE
DIMETHICONE
EDETATE DISODIUM
XANTHAN GUM
PYRITHIONE ZINC
SODIUM THIOSULFATE
WATER
MAGNESIUM ALUMINUM SILICATE
METHYLPARABEN

Product Characteristics
Color		Score
Shape		Size
Flavor		Imprint Code
Contains

Packaging
#	NDC	Package Description	Multilevel Packaging
1	42808-111-45	1 TUBE In 1 CARTON	contains a TUBE
1		45 g In 1 TUBE	This package is contained within the CARTON (42808-111-45)

Marketing Information
Marketing Category	Application Number or Monograph Citation	Marketing Start Date	Marketing End Date
unapproved drug other		08/01/2011

Labeler - Exact-Rx, Inc. (137953498)

Revised: 08/2011Exact-Rx, Inc.

More Sodium Sulfacetamide and Sulfur Aqueous Gel resources

Sodium Sulfacetamide and Sulfur Aqueous Gel Side Effects (in more detail)
Sodium Sulfacetamide and Sulfur Aqueous Gel Use in Pregnancy & Breastfeeding
Sodium Sulfacetamide and Sulfur Aqueous Gel Drug Interactions
Sodium Sulfacetamide and Sulfur Aqueous Gel Support Group
18 Reviews for Sodium Sulfacetamide and Sulfur Aqueous - Add your own review/rating

Compare Sodium Sulfacetamide and Sulfur Aqueous Gel with other medications

Acne
Rosacea
Seborrheic Dermatitis

Sunday, August 5, 2012

Tri-Vi-Flor with Iron

Generic Name: multivitamin with iron and fluoride (MUL tee VYE ta min with EYE urn and FLOOR ide)

Brand Names: MyKidz Iron FL, PhluoriVit with Iron, Poly Vitamin with Fluoride with Iron, Poly-Vi-Flor with Iron, Tri Vites with Fluoride and Iron, Tri-Vi-Flor with Iron

What is Tri-Vi-Flor with Iron (multivitamin with iron and fluoride)?

Multivitamins provide essential vitamins and minerals that are not taken in to the body through diet.

Iron is a mineral that helps maintain your body's red blood cells.

Fluoride strengthens tooth enamel, which helps prevent dental cavities. In most major U.S. communities, fluoride is put into the water supply.

Multivitamin with iron and fluoride is used as a supplement to the diet of infants and children who do not receive adequate fluoride through drinking water. Multivitamin with iron and fluoride is also used to prevent tooth decay in people treated with radiation, which may cause dryness of the mouth and increased risk of tooth decay.

Multivitamin with iron and fluoride may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Tri-Vi-Flor with Iron (multivitamin with iron and fluoride)?

Taking in too much fluoride can cause an irreversible condition called fluorosis. This condition can permanently damage teeth and possibly other cells in the body.

Be sure that a child using this medicine is not taking in extra amounts of fluoride by swallowing toothpaste, or drinking water from sources that contain adequate levels of fluoride.

Do not take this medication with milk, other dairy products, calcium supplements, or antacids that contain calcium. Calcium may cause your body to absorb less of the multivitamin with iron and fluoride. Avoid taking any other multivitamin product within 2 hours before or after you take multivitamin with iron and fluoride. Taking similar vitamin products together at the same time can result in a vitamin overdose or serious side effects.

What should I discuss with my healthcare provider before taking Tri-Vi-Flor with Iron (multivitamin with iron and fluoride)?

Taking in too much fluoride can cause an irreversible condition called fluorosis. This condition can permanently damage teeth and possibly other cells in the body.

Do not use this medicine without the advice of a doctor. Multivitamin with iron and fluoride should not be used if the level of fluoride in the drinking water is adequate (0.6 parts per million or higher). Check with your local water department if you are unsure about the level of fluoride in the drinking water. FDA pregnancy category C. It is not known whether this medication is harmful to an unborn baby. Before using multivitamin with iron and fluoride, tell your doctor if you are pregnant or plan to become pregnant during treatment. Multivitamin with iron and fluoride can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take Tri-Vi-Flor with Iron (multivitamin with iron and fluoride)?

Use this medication exactly as it was prescribed for you. Do not use the medication in larger amounts, or use it for longer than recommended by your doctor.

Take each dose of this medicine with a full glass of water.

The chewable tablet must be chewed or allowed to dissolve in the mouth before swallowing it. You may also allow the tablet to dissolve in drinking water, fruit juice, or infant formula (but not milk or other dairy products).

Do not give a chewable tablet to a child younger than 4 years old. The child may choke on the tablet. Use only liquid forms of this medicine in young children.

Measure the liquid form of multivitamin with iron and fluoride using a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one.

The liquid may also be mixed with water, fruit juice, or infant formula.

It is important to take multivitamin with iron and fluoride regularly to get the most benefit.

Brush teeth regularly, at least two times each day, or after meals. This will help prevent tooth discoloration.

Store this medication at room temperature away from moisture and heat. Do not allow the liquid to freeze.

Keep multivitamin with iron and fluoride in the original contain it came in. Storing multivitamin with iron and fluoride in a glass container can ruin the medication.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine. An overdose of this medicine can be fatal.

Overdose symptoms may include nausea, vomiting, stomach pain, diarrhea, drowsiness, fast heart rate, fainting, and seizure (convulsions).

What should I avoid while taking Tri-Vi-Flor with Iron (multivitamin with iron and fluoride)?

Avoid using other multivitamins or mineral supplements that also contain iron. Getting too much iron can cause serious medical problems or death.

Avoid taking any other multivitamin product within 2 hours before or after you take multivitamin with iron and fluoride. Taking similar vitamin products together at the same time can result in a vitamin overdose or serious side effects.

Be sure that a child using this medicine is not taking in extra amounts of fluoride by swallowing toothpaste, or drinking water from sources that contain adequate levels of fluoride.

Tri-Vi-Flor with Iron (multivitamin with iron and fluoride) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

This medication may cause the tooth enamel to become discolored. This is a rare side effect that has occurred mainly with large doses or long-term use of multivitamin with iron and fluoride. Stop using this medication and call your dentist or doctor at once if you notice any change in the appearance of your teeth.

Less serious side effects may include:

stomach upset;

headache; or

weakness.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Tri-Vi-Flor with Iron (multivitamin with iron and fluoride)?

There may be other drugs that can interact with multivitamin with iron and fluoride. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

More Tri-Vi-Flor with Iron resources

Tri-Vi-Flor with Iron Use in Pregnancy & Breastfeeding
Tri-Vi-Flor with Iron Drug Interactions
Tri-Vi-Flor with Iron Support Group
0 Reviews for Tri-Vi-Flor with Iron - Add your own review/rating

Multivitamin with Iron and Fluoride Drops MedFacts Consumer Leaflet (Wolters Kluwer)

Compare Tri-Vi-Flor with Iron with other medications

Dietary Supplementation

Where can I get more information?

Your pharmacist can provide more information about multivitamin with iron and fluoride.

Thursday, August 2, 2012

Trobicin

spectinomycin

Dosage Form: injectable suspension

For intramuscular Injection

Trobicin Description

Trobicin Sterile Powder contains spectinomycin hydrochloride which is an aminocyclitol antibiotic produced by a species of soil microorganism designated as Streptomyces spectabilis. Sterile spectinomycin hydrochloride is the pentahydrated dihydrochloride salt of spectinomycin. The structural formula is represented below:

Spectinomycin hydrochloride is isolated as a white to pale buff crystalline dihydrochloride pentahydrate powder, molecular weight 495, and is stable in the dry state for 36 months.

Trobicin - Clinical Pharmacology

Trobicin Sterile Powder is rapidly absorbed after intramuscular injection. A single, two-gram injection produces peak serum concentrations averaging about 100 mcg/mL at one hour; a single, four-gram injection produces peak serum concentrations averaging 160 mcg/mL at two hours. Average serum concentrations of 15 mcg/mL for the two-gram dose and 31 mcg/mL for the four-gram dose were present eight hours after dosing.

Microbiology

Spectinomycin hydrochloride is an inhibitor of protein synthesis in the bacterial cell; the site of action is the 30S ribosomal subunit.

In vitro studies have shown spectinomycin hydrochloride to be active against most strains of Neisseria gonorrhoeae (minimum inhibitory concentration <7.5 to 20 mcg/mL).

Definitive in vitro studies have shown no cross-resistance of N. gonorrhoeae between spectinomycin hydrochloride and penicillin. The antibiotic is not significantly bound to plasma protein.

Indications and Usage for Trobicin

Trobicin Sterile Powder is indicated in the treatment of acute gonorrheal urethritis and proctitis in the male and acute gonorrheal cervicitis and proctitis in the female when due to susceptible strains of Neisseria gonorrhoeae. Men and women with known recent exposure to gonorrhea should be treated as those known to have gonorrhea.

The in vitro susceptibility of Neisseria gonorrhoeae to spectinomycin hydrochloride can be tested by agar diluted methods. Trobicin Susceptibility Powder is available for this purpose and its package insert should be consulted for details.

To reduce the development of drug-resistant bacteria and maintain the effectiveness of Trobicin Sterile Powder and other antibacterial drugs, Trobicin Sterile Powder should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.

Contraindications

The use of Trobicin Sterile Powder is contraindicated in patients previously found hypersensitive to it.

Warnings

Spectinomycin hydrochloride is not effective in the treatment of syphilis. Antibiotics used in high doses for short periods of time to treat gonorrhea may mask or delay the symptoms of incubating syphilis. Since the treatment of syphilis demands prolonged therapy with any effective antibiotic, patients being treated for gonorrhea should be closely observed clinically. All patients with gonorrhea should have a serologic test for syphilis at the time of diagnosis. Patients treated with spectinomycin hydrochloride should have a follow-up serologic test for syphilis after three months.

Contains benzyl alcohol. Benzyl alcohol has been reported to be associated with a fatal "Gasping Syndrome" in premature infants and an increased incidence of neurologic and other complications.

Precautions

The usual precautions should be observed with atopic individuals.

The clinical effectiveness of Trobicin Sterile Powder should be monitored to detect evidence of development of resistance by Neisseria gonorrhoeae.

Prescribing Trobicin Sterile Powder in the absence of a proven or strongly suspected bacterial infection or a prophylactic indication is unlikely to provide benefit to the patient and increases the risk of the development of drug-resistant bacteria.

Information for Patients

Patients should be counseled that antibacterial drugs including Trobicin Sterile Powder should only be used to treat bacterial infections. They do not treat viral infections (e.g., the common cold). When Trobicin Sterile Powder is prescribed to treat a bacterial infection, patients should be told that although it is common to feel better early in the course of therapy, the medication should be taken exactly as directed. Skipping doses or not completing the full course of therapy may (1) decrease the effectiveness of the immediate treatment and (2) increase the likelihood that bacteria will develop resistance and will not be treatable by Trobicin Sterile Powder or other antibacterial drugs in the future.

Carcinogenesis, Mutagenesis, Impairment of Fertility

Genotoxicity of spectinomycin hydrochloride was evaluated in six assay test systems including two Ames tests, two micronucleus tests in mice, unscheduled DNA synthesis in rat primary hepatocytes, and a chromosomal aberration test in Chinese hamster ovary cells. Spectinomycin was not shown to be mutagenic or genotoxic in these tests.

No adverse effects on fertility or general reproductive performance were observed when spectinomycin was administered subcutaneously to rats at dose levels up to 300 mg/kg (equivalent to the recommended maximum human dose based on mg/m2). A three-generation reproduction study in rats administered spectinomycin hydrochloride orally at dose levels up to 400 mg/kg (equivalent to the recommended maximum human dose based on mg/m2) produced no evidence of drug-induced toxicity during growth, gestation, or lactation periods of any parental generation. Pregnancy rates of the 400 mg/kg/day groups were consistently lower than those of the control groups. A histopathological examination of the testes and ovaries of the third generation animals was normal.

Pregnancy

Teratogenic Effects

Pregnancy Category B

Spectinomycin was not teratogenic or embryocidal when orally or subcutaneously administered to rats at doses of 300 mg/kg/day (equivalent to the recommended maximum human dose based on mg/m2). No teratogenic effects were observed when spectinomycin was administered intraperitoneally to mice or rats at dose levels of 400 or 1600 mg/kg/day, respectively. Spectinomycin was administered intramuscularly or subcutaneously to pregnant rabbits at dose levels up to 300 mg/kg/day (equivalent to the recommended maximum human dose based on mg/m2). Embryonic and fetal development were unaffected by treatment. Since there are no controlled studies of spectinomycin in pregnant women, and because animal reproduction studies are not always predictive of human responses, spectinomycin should be used during pregnancy only if clearly needed.

Nursing Mothers

It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when spectinomycin is administered to a nursing woman.

Pediatric Use

Safety and effectiveness in the pediatric population have not been established. (See WARNINGS.)

Adverse Reactions

The following reactions were observed during the single dose clinical trials: soreness at the injection site, urticaria, dizziness, nausea, chills, fever and insomnia.

During multiple dose subchronic tolerance studies in normal human volunteers, the following were noted: a decrease in hemoglobin, hematocrit and creatinine clearance; elevation of alkaline phosphatase, BUN and SGPT. In single and multiple dose studies in normal volunteers, a reduction in urine output was noted. Extensive renal function studies demonstrated no consistent changes indicative of renal toxicity.

A few cases of anaphylaxis or anaphylactoid reactions have been reported. If serious allergic reactions occur, the usual agents (epinephrine, corticosteroids, and/or antihistamines) should be available for emergency use. In cases of severe anaphylaxis, airway support and oxygen may also be required.

Overdosage

Information on overdosage in humans is not available. Hemodialysis has been reported to aid in the removal of intravenously administered spectinomycin from the body.

Kusumi R, Metzler C, Fass R; Pharmacokinetics of Spectinomycin in Volunteers with Renal Insufficiency, Chemotherapy, 27:95–98 (1981).

Trobicin Dosage and Administration

Preparation of Drug for Intramuscular Injection

Trobicin Sterile Powder, 2 grams: reconstitute with 3.2 mL of the accompanying diluent.1

Shake vials vigorously immediately after adding diluent and before withdrawing dose. It is recommended that disposable syringes and needles be used to avoid contamination with penicillin residue, especially when treating patients known to be highly sensitive to penicillin. Use of a 20-gauge needle is recommended.

1: Bacteriostatic Water for Injection with Benzyl Alcohol 0.945% w/v added as preservative.

Dosage

Intramuscular injections should be made deep into the upper outer quadrant of the gluteal muscle.

Adults (Men and Women)—Inject 5 mL intramuscularly for a 2-gram dose. This is also the recommended dose for patients being treated after failure of previous antibiotic therapy.

In geographic areas where antibiotic resistance is known to be prevalent, initial treatment with 4 grams (10 mL) intramuscularly is preferred. The 10-mL injection may be divided between two gluteal injection sites.

STORAGE CONDITIONS

Store unreconstituted product at controlled room temperature 20° to 25°C (68° to 77°F) [see USP]. Store prepared suspension at controlled room temperature 20° to 25°C (68° to 77°F) and use within 24 hours.

How is Trobicin Supplied

Contains benzyl alcohol. (See WARNINGS.)

Trobicin Sterile Powder is available as:

Trobicin Sterile Powder, 2-gram vial NDC 0009-0566-01—with one ampoule of Bacteriostatic Water for Injection with Benzyl Alcohol 0.945% w/v added as preservative. When reconstituted with 3.2 mL of the accompanying diluent, each vial yields a sufficient quantity for withdrawal of 5 mL of a suspension containing 400 mg spectinomycin per mL (as the hydrochloride). Five mL provides 2 grams spectinomycin. For intramuscular use only.

Trobicin Susceptibility Powder—100 mg. See package insert for in vitro testing procedure.

Rx only

LAB-0230-3.0

Revised August 2006

Trobicin
spectinomycin kit

Product Information
Product Type	HUMAN PRESCRIPTION DRUG	NDC Product Code (Source)	0009-0566

Packaging
#	NDC	Package Description	Multilevel Packaging
1	0009-0566-01	1 KIT In 1 PACKAGE, COMBINATION	None

QUANTITY OF PARTS
Part #	Package Quantity	Total Product Quantity
Part 1	1 VIAL	5 MILLILITER in 1
Part 2	1 AMPULE	3.2 MILLILITER in 1

Part 1 of 2

Trobicin
spectinomycin hydrochloride injection, powder, for suspension

Product Information

Route of Administration	INTRAMUSCULAR	DEA Schedule

INGREDIENTS
Name (Active Moiety)	Type	Strength
spectinomycin hydrochloride (spectinomycin)	Active	400 MILLIGRAM In 1 MILLILITER

Product Characteristics
Color		Score
Shape		Size
Flavor		Imprint Code
Contains

Packaging
#	NDC	Package Description	Multilevel Packaging
1		5 mL (MILLILITER) In 1 VIAL	None

Part 2 of 2

BACTERIOSTATIC WATER
water injection, solution

Product Information

Route of Administration	INTRAMUSCULAR	DEA Schedule

INGREDIENTS
Name (Active Moiety)	Type	Strength
Water	Inactive
Benzyl Alcohol	Inactive

Product Characteristics
Color		Score
Shape		Size
Flavor		Imprint Code
Contains

Packaging
#	NDC	Package Description	Multilevel Packaging
1		3.2 mL (MILLILITER) In 1 AMPULE	None

Revised: 03/2007Pharmacia and Upjohn, Co.

More Trobicin resources

Trobicin Side Effects (in more detail)
Trobicin Drug Interactions
Trobicin Support Group
0 Reviews for Trobicin - Add your own review/rating

Trobicin Concise Consumer Information (Cerner Multum)

Trobicin Monograph (AHFS DI)

Trobicin Advanced Consumer (Micromedex) - Includes Dosage Information

Spectinomycin Professional Patient Advice (Wolters Kluwer)

Compare Trobicin with other medications

Gonococcal Infection
Gonococcal Infection, Disseminated
Gonococcal Infection, Uncomplicated

Wednesday, August 1, 2012

Stalevo 150

Generic Name: carbidopa, entacapone, and levodopa (KAR bi DOE pa, en TAK a pone, LEE voe DOE pa)

Brand Names: Stalevo 100, Stalevo 125, Stalevo 150, Stalevo 200, Stalevo 50, Stalevo 75

What is Stalevo 150 (carbidopa, entacapone, and levodopa)?

Levodopa is converted to a chemical called dopamine (DOE pa meen) in the brain. Symptoms of Parkinson's disease may be caused by low levels of dopamine in the brain. Carbidopa helps prevent the breakdown of levodopa before it can reach the brain and take effect. Entacapone increases levels of levodopa in the body.

The combination of carbidopa, entacapone, and levodopa is used to treat Parkinson symptoms such as muscle stiffness, tremors, spasms, and poor muscle control.

Carbidopa, entacapone, and levodopa may also be used for purposes not listed in this medication guide.

What is the most important information I should know about Stalevo 150 (carbidopa, entacapone, and levodopa)?

You should not use this medication if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days.

You should not take this medication if you are allergic to carbidopa (Lodosyn), entacapone (Comtan), or levodopa (Larodopa), or if you have narrow-angle glaucoma, unusual skin lesions, or a history of skin cancer.

Tell your doctor about all of your medical conditions, especially heart disease, high blood pressure, asthma or other breathing problems, liver or kidney disease, a hormonal disease, an ulcer, glaucoma, or mental illness. Also tell your doctor about all the medications you use.

It may take up to several weeks of using carbidopa, entacapone, and levodopa before your symptoms improve. Talk with your doctor if your symptoms do not improve or if the effects of this medication seem to wear off quickly in between doses. Do not stop using carbidopa, entacapone, and levodopa without first talking to your doctor.

What should I discuss with my healthcare provider before taking Stalevo 150 (carbidopa, entacapone, and levodopa)?

Do not take this medication if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days.

You should not take this medication if you are allergic to carbidopa (Lodosyn), entacapone (Comtan), or levodopa (Larodopa), or if you have:

narrow-angle glaucoma;

unusual skin lesions that have not been checked by a doctor; or

a history of malignant melanoma (skin cancer).

To make sure you can safely take this medication, tell your doctor if you have any of these other conditions:

heart disease, high blood pressure, coronary artery disease, a heart rhythm disorder, or a prior heart attack;

asthma, chronic obstructive pulmonary disease (COPD), or other breathing disorder;

kidney disease, liver disease, or bile duct obstruction;

an endocrine (hormonal) disease;

a stomach or intestinal ulcer;

glaucoma; or

depression or other mental illness.

You may have increased sexual urges, unusual urges to gamble, or other intense urges while taking this medication. Talk with your doctor if you believe you have any intense or unusual urges while taking this medicine.

Carbidopa, entacapone, and levodopa may cause hallucinations (the sensation of hearing or seeing something that is not there). Call your doctor if you experience hallucinations.

Some people taking Parkinson's disease medications have developed skin cancer (melanoma). However, people with Parkinson's disease may have a higher risk of melanoma. Talk to your doctor about this risk and what skin symptoms to watch for. You may need to have regular skin exams.

FDA pregnancy category C. It is not known whether carbidopa, entacapone, and levodopa will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. Carbidopa, entacapone, and levodopa may pass into breast milk and could harm a nursing baby. You should not breast-feed while you are taking carbidopa, entacapone, and levodopa.

How should I take Stalevo 150 (carbidopa, entacapone, and levodopa)?

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label. Take your medicine at regular intervals to keep a steady amount of the drug in your body at all times.

Drink plenty of liquids while you are taking this medication. It may take up to several weeks before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve after a few weeks of treatment. Also tell your doctor if the effects of this medication seem to wear off quickly in between doses. Call your doctor if you have ongoing vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking this medication, which can lead to severely low blood pressure or a serious electrolyte imbalance. Do not stop using carbidopa, entacapone, and levodopa without first talking to your doctor. You may need to use less and less before you stop the medication completely.

This medication can cause unusual results with certain medical tests. Tell any doctor who treats you that you are using carbidopa, entacapone, and levodopa.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include weakness, loss of coordination, trouble breathing, fainting, or seizure (convulsions).

What should I avoid while taking Stalevo 150 (carbidopa, entacapone, and levodopa)?

Carbidopa, entacapone, and levodopa may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

Avoid taking iron supplements or eating a diet that is high in protein (protein sources include meat, eggs, and cheese). These things can make it harder for your body to digest and absorb carbidopa, entacapone, and levodopa.

Stalevo 150 (carbidopa, entacapone, and levodopa) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have a serious side effect such as:

nausea, sweating, feeling like you might pass out (especially when you first start taking this medication);

depression, confusion, hallucinations, unusual thoughts or behavior, thoughts about hurting yourself;

worsening symptoms such as tremors, twitching or uncontrollable movements of your eyes, lips, tongue, face, arms, or legs;

severe or ongoing diarrhea, extreme thirst, increased urination, weight loss, leg discomfort, muscle weakness or limp feeling, uneven heart rate;

feeling very thirsty or hot, being unable to urinate, heavy sweating, or hot and dry skin;

fast, pounding, or uneven heartbeats;

chest pain or heavy feeling, pain spreading to the arm or shoulder, general ill feeling;

tight feeling in your chest, new or worsening cough, fever, trouble breathing;

easy bruising or bleeding, bloody or tarry stools, coughing up blood;

pain or burning when you urinate; or

unexplained muscle pain, tenderness, or weakness.

Less serious side effects may include:

stomach pain or upset, loss of appetite, constipation;

dry mouth, changes in your sense of taste;

unusual skin changes. mild rash or itching;

dizziness or drowsiness, headache, blurred vision;

muscle cramps, back pain; or

agitation or anxiety, sleep problems (insomnia), strange dreams.

You may notice that your sweat, urine, or saliva appears dark in color, such as red, brown, or black. This is not a harmful side effect, but it may cause staining of your clothes or bed sheets.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Stalevo 150 (carbidopa, entacapone, and levodopa)?

Cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression or anxiety can add to sleepiness caused by carbidopa, entacapone, and levodopa. Tell your doctor if you regularly use any of these other medicines, or any other Parkinson's medications.

Tell your doctor about all other medicines you use, especially:

apomorphine (Apokyn);

cholestyramine (Prevalite, Questran);

dobutamine (Dobutrex);

epinephrine (Epi-Pen, and others);

isoniazid (for treating tuberculosis);

isoproterenol (Isuprel, Medihaler-Iso);

methyldopa (Aldomet);

metoclopramide (Reglan);

papaverine (Pavabid, Papacon, Pavagen, Pavacot);

phenytoin (Dilantin);

probenecid (Benemid);

blood pressure medication;

an antibiotic such as ampicillin, chloramphenicol, erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin, Pediazole, and others), or rifampin (Rifadin, Rifater, Rifamate);

an antidepressant such as amitriptyline (Elavil, Vanatrip, Limbitrol), doxepin (Sinequan), imipramine (Janimine, Tofranil), nortriptyline (Pamelor), and others; or

medicines to treat psychiatric disorders, such as chlorpromazine (Thorazine), haloperidol (Haldol), prochlorperazine (Compazine), risperidone (Risperdal), and others.

This list is not complete and other drugs may interact with carbidopa, entacapone, and levodopa. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More Stalevo 150 resources

Stalevo 150 Side Effects (in more detail)
Stalevo 150 Use in Pregnancy & Breastfeeding
Drug Images
Stalevo 150 Drug Interactions
Stalevo 150 Support Group
0 Reviews for Stalevo50 - Add your own review/rating

Stalevo 150 Advanced Consumer (Micromedex) - Includes Dosage Information

Carbidopa/Entacapone/Levodopa MedFacts Consumer Leaflet (Wolters Kluwer)

Compare Stalevo 150 with other medications

Parkinson's Disease

Where can I get more information?

Your pharmacist can provide more information about carbidopa, entacapone, and levodopa.

See also: Stalevo50 side effects (in more detail)

Tuesday, July 31, 2012

Niacinamide Gel

Pronunciation: NYE-a-sin-a-mide
Generic Name: Niacinamide
Brand Name: Nicomide-T

Niacinamide Gel is used for:

Treating acne.

Niacinamide Gel is a vitamin B supplement. Exactly how Niacinamide Gel works is unknown.

Do NOT use Niacinamide Gel if:

you are allergic to any ingredient in Niacinamide Gel

Contact your doctor or health care provider right away if any of these apply to you.

Before using Niacinamide Gel:

Some medical conditions may interact with Niacinamide Gel. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding

if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

if you have allergies to medicines, foods, or other substances

Some MEDICINES MAY INTERACT with Niacinamide Gel. However, no specific interactions with Niacinamide Gel are known at this time.

Ask your health care provider if Niacinamide Gel may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Niacinamide Gel:

Use Niacinamide Gel as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Wash the affected area with a mild cleanser or other cleansing product prescribed by your doctor and completely dry.

Apply a thin layer of the medicine to the affected area twice daily or as directed by your doctor. Gently rub the medicine in until it is evenly distributed.

Wash your hands immediately after using Niacinamide Gel.

If you miss a dose of Niacinamide Gel, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Niacinamide Gel.

Important safety information:

Niacinamide Gel is for external use only. Avoid getting Niacinamide Gel in your eyes. If you get Niacinamide Gel in your eyes, rinse thoroughly with cool tap water.

Follow up with your doctor after 8 to 12 weeks to monitor your progress.

Do not use any other medicines or special cleansers on your skin unless your doctor instructs you otherwise. Makeup and other acne medicines may be applied over Niacinamide Gel as directed by your doctor.

PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Niacinamide Gel while you are pregnant. It is not known if Niacinamide Gel is found in breast milk after topical use. If you are or will be breast-feeding while you use Niacinamide Gel, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Niacinamide Gel:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dry skin.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); irritation.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of Niacinamide Gel:

Store Niacinamide Gel at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not freeze. Do not store in the bathroom. Keep Niacinamide Gel out of the reach of children and away from pets.

General information:

If you have any questions about Niacinamide Gel, please talk with your doctor, pharmacist, or other health care provider.

Niacinamide Gel is to be used only by the patient for whom it is prescribed. Do not share it with other people.

If your symptoms do not improve or if they become worse, check with your doctor.

Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Niacinamide Gel. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

More Niacinamide resources

Niacinamide Use in Pregnancy & Breastfeeding
Niacinamide Support Group
0 Reviews for Niacinamide - Add your own review/rating

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Rosacea